Desenvolvimento de dispositivo portátil de VNI com nível único de pressão intervalada: validação de componentes em ambiente de laboratório

Abstract

INTRODUCTION: The lung's main function is to allow the cyclical exchange of vital gases between the environment and blood capillaries. Some diseases can interfere with this mechanism, which may lead to the need for ventilatory assistance. MV is a ventilatory therapy that supports or replaces the breathing of the patient who needs it. MV can be invasive or non-invasive. Non-invasive mechanical ventilation is defined as ventilatory support that does not require an orotracheal tube or tracheostomy, being used through an external interface. There is a great therapeutic demand for the use of NIV, requiring the development of new modalities, aiming for efficacy, safety and comfort. OBJECTIVE: validate, in the laboratory, the main components that meet the basic requirements for the development of a portable NIV device, with a single level of interval pressure. METHODOLOGY: This project is based on the TRL scale (technological maturity level) that assists technological development through clearly delimited, described and standardized levels, until the product is ready for use and commercialization. Following the scale, the TRL 4 level validation requirements were carried out (phase of technological development that validates the main components in the laboratory). To compose the proposed technology, the main basic components were chosen in order to validate the performance of the flow generator and pressure sensor. To measure and validate the main basic functions, an IML-PF-300 IMT MEDICAL flow analyzer and a GM1351 B-Max decibel meter were used. A closed system was developed with the purpose of evaluating the performance of components working together, enabling the development of the equipment. RESULTS: Validation tests of the flow generator showed excellent performance, reaching maximum flow greater than 170L/min and maximum pressure greater than 55cmH2O. The noise detected was in the tolerated range (up to 30dBA at 10cmH2O, with a tolerance of 6dBA). The pressure sensor was able to measure the pressures generated in the system, maintaining a variation of less than 0.5cmH2O from that measured by the analyzer. CONCLUSION: it can be concluded that the work achieved the objectives listed, with the main basic components (proposed to compose the portable single-level NIV device with interval pressure), fulfilling the performance requirements for laboratory validation, with them working together.