Efeito do exercício físico com videogame ativo sobre os biomarcadores de estresse oxidativo em adolescentes com sobrepeso ou obesidade

Abstract

Introduction: Overweight and obesity are defined by the abnormal accumulation of body fat, which can cause damage to the health of individuals, the regular practice of physical exercises becomes essential to prevent excessive weight gain and obesity. Among the mechanisms related to the pathogenesis of chronic non-communicable diseases are changes in oxidative metabolism, which indicates an association between the breakdown of oxidative metabolism homeostasis. Oxidative stress is the imbalance between the production of oxidizing substances and antioxidant defenses, such as increased production of Reactive Oxygen Species, which can result in cellular and tissue damage. Objective: to investigate the impact of physical exercise on oxidative stress biomarkers in overweight or obese adolescents. Methods: quasi experimental intervention study, carried out with 46 adolescents aged 15 to 19 years, through intervention activity with active video game for fifty minutes, three times a week, for a period of eight weeks, between June and December 2016, in two public schools in the municipality of Campina Grande-PB. Socioeconomic and demographic variables and biomarkers of oxidative stress (total antioxidant capacity and malonaldehyde) were evaluated. Descriptive analysis was performed and the boxplot was used to assess the distribution of data, Shapiro-Wilks hypothesis tests (p = 0.05) and compared using the Student t test (p <0.00) 1, to analyze the malonaldehyde was used t test (p = 0.048). Results: there was a decrease in the total antioxidant capacity and an increase in malonaldehyde in the post-intervention samples. The adolescents showed insufficient antioxidant capacity to protect the body from the production of reactive oxygen species, caused by physical exercise with an active video game, which may be linked to other external causes such as physical inactivity, food, increased cortisol, which when performing physical activity due to increased oxygen consumption there was a failure in antioxidant mechanisms. Conclusion: it is necessary that adolescents continue to perform physical activity regularly so that the antioxidant mechanisms are increased, reducing the effects of oxidative stress.