Estudo comparativo da eficácia in vitro de pastas intracanal comercializadas e formuladas a partir de plantas medicinais do semiárido brasileiro

Abstract

The objective of this study was to evaluate in vitro experimental drugs made from plants of the Brazilian semiarid region, Schinopsis brasiliensis Engl. and Ximenia americana L., comparing its effectiveness with commercial medications. Hydroalcoholic extracts were prepared from six medicinal plants (Schinopsis brasiliensis Engl., Ximenia americana L., Cereus jamacaru DC., Croton campestres ST. Hill, Spondias mombin, Zornia reticulata SM.), which were subjected to an Enterococcus faecalis microbiological screening by agar dilution method, cylinder technique. The two groups of greater efficiency, Schinopsis brasiliensis Engl. and Ximenia americana L., were nebulized and potency was evaluated by the same method. In vitro contamination with E. faecalis was performed in teeth for 60 days with bacterial growth evaluated by scanning electron microscopy, optical microscopy and microbiological tests. After the inoculation period, the teeth were irrigated, dried and filled with different drugs: 1 - experimental S. brasiliensis paste, 2 - experimental X. americana paste, 3 - Calen ® paste and 4 – CTZ paste. The pastes removal and analysis of the results were performed after 8 and 28 days after their application. The results showed that the X. americana paste had greater efficacy and was able to inhibit the growth of E. faecalis after 28 days of treatment, compared with the other studied pastes, with CTZ exception, that presented the best results during the entire treatment period.